A 2019 study evaluated the efficacy of a bupivacaine liposome injectable suspension (BLIS) for controlling pain in cats after undergoing an ovariohysterectomy. Forty-seven cats were included in the study, with half receiving a local block of BLIS around the incision and the other half receiving a standard protocol of a bupivacaine block followed by oral medication.

Cats in both groups had low pain scores up to 68 hours after surgery. The researchers concluded that the pain control imparted by BLIS is equivalent to that provided by bupivacaine block followed by oral analgesics and reduces the need for continued post-operative drug administration. n

Gordon-Evans, W. J., Suh, H. Y., & Guedes, A. G. (2019). Controlled, non-inferiority trial of bupivacaine