Rapamycin to Treat Hypertrophic Cardiomyopathy

FDA grants conditional approval to a targeted form of the drug

Joshua Stern, DVM, PhD, of North Carolina State University, has been studying a formulation of the medication rapamycin (sirolimus) that has been shown to forestall progressive ventricular thickening over a six-month period in cats with hypertrophic cardiomyopathy (HCM). Based in part upon these initial findings, the FDA recently granted conditional approval for the use of this drug in cats with HCM, and subjects are currently being enrolled for a follow-up 12-month clinical trial (the HALT HCM study).

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